Rac-[(3r,4s)-1-benzyl-4-(4-fluorophenyl)piperidin-3-yl]methanol, trans CAS 188869-25-2
| CAS No. | 188869-25-2 |
| Molecular Formula | C19H22FNO |
| Molecular Weight | 299.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rac-[(3r,4s)-1-benzyl-4-(4-fluorophenyl)piperidin-3-yl]methanol, trans.
Rac-[(3r,4s)-1-benzyl-4-(4-fluorophenyl)piperidin-3-yl]methanol, trans (CAS 188869-25-2), molecular formula C19H22FNO and molecular weight 299.38 g/mol, is a CATO reference standard with documented purity and traceability.
Rac-[(3r,4s)-1-benzyl-4-(4-fluorophenyl)piperidin-3-yl]methanol, trans (C19H22FNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Rac-[(3r,4s)-1-benzyl-4-(4-fluorophenyl)piperidin-3-yl]methanol, trans meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22FNO |
| Molecular Weight | 299.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- cis-tert-butyl 3-(4-fluorobenzoyl)cyclobytylcarbamate (CAS 1630907-38-8)
- 1-Benzyl-4-(2-fluorobenzyl)piperidin-4-ol (CAS 71916-70-6)
- trans-tert-butyl 3-(4-fluorobenzoyl)cyclobytylcarbamate (CAS 1630906-41-0)
- 3-((4-(Sec-butyl)phenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 882748-27-8)
- (3-(1-((Tert-butoxycarbonyl)amino)-3-methylbutyl)oxetan-3-yl)glycine (CAS 2199282-78-3)
- 1-(p-tolyl)hexahydropyrimidine-2,4-dione (CAS 19144-80-0)
- 4-Amino-3-methylbiphenyl (CAS 63019-98-7)
- 6-O-beta-D-Fructofuranosyl-D-fructose (CAS 17669-60-2)
- 1,2-Bis(3-fluorophenyl)hydrazine (CAS 331-20-4)
- Methyl 2-amino-2-methyl-4-(2-methyl-1h-imidazol-1-yl)butanoate (CAS 1250109-06-8)
- 1-Ethyl-5-oxo-2-(3,4,5-trifluorophenyl)pyrrolidine-3-carboxamide (CAS 1461708-26-8)
- Methyl 3-amino-2-methyl-3-oxopropanoate (CAS 93823-25-7)
- Isoetharine HCl (CAS 50-96-4)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
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