rel-tert-Butyl (3R,4R)-4-cyano-3-hydroxypiperidine-1-carboxylate CAS 188879-53-0
| CAS No. | 188879-53-0 |
| Molecular Formula | C11H18N2O3 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, rel-tert-Butyl (3R,4R)-4-cyano-3-hydroxypiperidine-1-carboxylate (C11H18N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 226.27 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies rel-tert-Butyl (3R,4R)-4-cyano-3-hydroxypiperidine-1-carboxylate (CAS 188879-53-0), a certified reference material (molecular formula C11H18N2O3, MW 226.27 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18N2O3 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 1-([1,1'-Biphenyl]-4-yloxy)propan-2-one (CAS 18859-38-6)
- Methyl 2'-methyl[1,1'-biphenyl]-2-carboxylate (CAS 188943-06-8)
- Ethyl 1-(4-hydroxypentyl)-1H-pyrazole-4-carboxylate (CAS 1882719-97-2)
- Ethyl (4aS,8aR)-2-oxooctahydro-1,6-naphthyridine-6(2H)-carboxylate (CAS 1890133-99-9)
- 3-Methoxy-3-methylbenzophenone (CAS 71372-40-2)
- 1-Phenethyl-N-(m-tolyl)piperidin-4-amine (CAS 99918-45-3)
- 1-Bromo-2-iodo-3-methoxy-5-methylbenzene (CAS 1208077-51-3)
- (6-Methoxypyridin-2-yl)(2-(trifluoromethyl)phenyl)methanone (CAS 1187165-94-1)
- N-[3,5-Bis(trifluoromethyl)phenyl]-2-(4-phenylpiperazin-1-yl)acetamide (CAS 329778-87-2)
- 5-Cyclopropylpentan-2-ol (CAS 1523058-85-6)
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- N-(1-(2,5-Dichlorophenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)acetamide (CAS 87820-16-4)
- 1-(3-Nitropyridin-2-yl)piperidine-4-carbonitrile (CAS 671191-99-4)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
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