(R)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione CAS 1889291-53-5
| CAS No. | 1889291-53-5 |
| Molecular Formula | C11H6BrNO4 |
| Molecular Weight | 296.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 296.07 g/mol gives (R)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(R)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione (CAS 1889291-53-5) is a high-purity analytical reference standard with the molecular formula C11H6BrNO4 and a molecular weight of 296.07 g/mol.
The molecular framework of (R)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione (C11H6BrNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6BrNO4 |
| Molecular Weight | 296.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- (S)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione (CAS 1889291-05-7)
- 5-Bromospiro[chroman-2,4'-piperidin]-4-one (CAS 1241953-09-2)
- 6-Bromospiro[chroman-2,4'-piperidin]-4-one (CAS 690632-08-7)
- 6-Bromospiro[chromane-2,1'-cyclohexan]-4-one (CAS 223416-26-0)
- 6'-Bromospiro[cyclohexane-1,3'-pyrrolo[3,2-b]pyridine]-2',4(1'H)-dione (CAS 1190862-23-7)
- 5'-Bromospiro[imidazolidine-4,1'-[1H]indene]-2,3',5(2'H)-trione (CAS 1889290-24-7)
- (S)-5'-Bromospiro[imidazolidine-4,1'-indene]-2,3',5(2'H)-trione (CAS 1889290-55-4)
- 6-Bromospiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one (CAS 92926-60-8)
Recommended Standards
- 1-Bromo-3-(1,1-difluoro-2-methoxyethyl)-5-nitrobenzene (CAS 2883760-09-4)
- 2-(4-Bromo-6-(difluoromethyl)-3-methoxypyridin-2-yl)acetic acid (CAS 1806912-40-2)
- 5-(2-Bromo-4-nitrophenyl)furan-2-carbaldehyde (CAS 327049-95-6)
- 2-(2-Bromo-3-(difluoromethyl)-6-methoxypyridin-4-yl)acetic acid (CAS 1806911-80-7)
- 2-((5-(Phenoxymethyl)-1,3,4-oxadiazol-2-yl)thio)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 948263-58-9)
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- N-(1-Acetyl-1H-indazol-6-yl)acetamide (CAS 95091-98-8)
- 6-(1-Tosylpyrrolidin-2-yl)quinoline (CAS 1355201-48-7)
- (9H-carbazol-9-yl)(phenyl)methanone (CAS 19264-68-7)
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- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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