2-(Difluoromethyl)pyridin-4-amine hydrochloride CAS 1890194-45-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1890194-45-2
Molecular FormulaC6H6F2N2
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)pyridin-4-amine hydrochloride CAS 1890194-45-2 chemical structure

Description

The occurrence of 2-(Difluoromethyl)pyridin-4-amine hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Difluoromethyl)pyridin-4-amine hydrochloride (CAS 1890194-45-2), molecular formula C6H6F2N2HCl and molecular weight 180.58 g/mol, is a CATO reference standard with documented purity and traceability.

2-(Difluoromethyl)pyridin-4-amine hydrochloride (C6H6F2N2HCl) contains a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(Difluoromethyl)pyridin-4-amine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H6F2N2 HCl
Molecular Weight180.58 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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