Diethyl 2-bromo-3-oxosuccinate CAS 18903-16-7
| CAS No. | 18903-16-7 |
| Molecular Formula | C8H11BrO5 |
| Molecular Weight | 267.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Diethyl 2-bromo-3-oxosuccinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Diethyl 2-bromo-3-oxosuccinate (CAS 18903-16-7) is a high-purity analytical reference standard with the molecular formula C8H11BrO5 and a molecular weight of 267.07 g/mol.
Structurally, Diethyl 2-bromo-3-oxosuccinate (C8H11BrO5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 267.07 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H11BrO5 |
| Molecular Weight | 267.07 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
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Recommended Standards
- 2-(Aminomethyl)-3-bromo-6-(difluoromethyl)pyridine-4-methanol (CAS 1806999-39-2)
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- 2-(Aminomethyl)-3-bromo-4-(difluoromethyl)pyridine-6-methanol (CAS 1806970-00-2)
- 3-(Bromomethyl)-2,4-difluoro-1,5-dimethoxybenzene (CAS 1956324-83-6)
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- N-benzyl-1-(2,6-dichlorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 339008-65-0)
- 2,3-Difluoro-6-(trifluoromethoxy)phenol (CAS 2386799-38-6)
- 3-O-Acetyl Ezetimibe-d4 (CAS 1217642-08-4)
- Tetrahydro-2H-thiopyran-4-carboxamide (CAS 167011-48-5)
- 1,1-Difluoroacetone oxime (CAS 433-49-8)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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