2-Methylthiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione CAS 18903-26-9
| CAS No. | 18903-26-9 |
| Molecular Formula | C6H5N3O2S |
| Molecular Weight | 183.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Methylthiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione (C6H5N3O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Methylthiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione (CAS 18903-26-9), a certified reference material (molecular formula C6H5N3O2S, MW 183.19 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Methylthiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5N3O2S |
| Molecular Weight | 183.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylthiazolo Standards
- 1-(6-Methylthiazolo[3,2-b][1,2,4]triazol-5-yl)ethanol (CAS 478080-55-6)
- 6-Methylthiazolo[4,5-b]pyridine-2-thiol (CAS 586409-05-4)
- 1-(6-Methylthiazolo[3,2-b][1,2,4]triazol-5-yl)ethanone (CAS 187597-18-8)
- 2-Methylthiazolo[4,5-b]pyridine-5-carbaldehyde (CAS 2407332-31-2)
- N-(6-Methylthiazolo[3,2-b][1,2,4]triazol-2-yl)acetamide (CAS 62032-92-2)
- 2-Methylthiazolo[4,5-d]pyrimidin-7(6H)-one (CAS 856938-66-4)
- 2-Methylthiazolo[5,4-d]pyrimidin-7-ol (CAS 5021-51-2)
- 3-Methylthiazolo[4,5-c]pyridazin-6(1H)-one (CAS 82608-23-9)
Recommended Standards
- 5-cyanopyridine-3-sulfonamide (CAS 1803597-63-8)
- (2-(Aminomethyl)phenyl)dimethylphosphine oxide (CAS 2287298-64-8)
- methyl 3-azidothiophene-2-carboxylate (CAS 158878-93-4)
- (2-Amino-4-methylphenyl)dimethylphosphine oxide (CAS 2361982-50-3)
- 2-(2,6-dioxo-3-piperidyl)-5-(5-hydroxypent-1-ynyl)isoindoline-1,3-dione (CAS 2357113-47-2)
- N,N-Dimethyl-5-(oxazol-5-yl)-2-phenylpyrimidin-4-amine (CAS 823796-27-6)
- (S)-1-(4-iodophenyl)ethane-1,2-diol (CAS 647026-57-1)
- 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 22276-95-5)
- 2-Chloro-5-(hydroxymethyl)phenylboronic Acid (CAS 1003042-59-8)
- Quinazoline-8-carboxamide (CAS 1823917-59-4)
- Nickel(II) bromide hydrate (CAS 313223-18-6)
- (2,4-Difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 2121511-74-6)
- Ethyl 4-(5-bromopentyloxy)benzoate (CAS 96517-13-4)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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