4-(Difluoromethyl)thiazol-2-amine hydrochloride CAS 1891208-44-8
| CAS No. | 1891208-44-8 |
| Molecular Formula | C4H4F2N2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Difluoromethyl)thiazol-2-amine hydrochloride (C4H4F2N2SHCl) is characterized by a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-(Difluoromethyl)thiazol-2-amine hydrochloride (CAS 1891208-44-8), a certified reference material (molecular formula C4H4F2N2SHCl, MW 186.60 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Difluoromethyl)thiazol-2-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4F2N2S HCl |
| Molecular Weight | 186.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 2-(2-(Difluoromethyl)phenyl)acetic acid (CAS 1000517-62-3)
- 2-[4-(difluoromethyl)phenyl]acetic acid (CAS 1000524-74-2)
- 2-(4-(Difluoromethyl)phenyl)acetonitrile (CAS 1000529-64-5)
- 2-(3-(Difluoromethyl)phenyl)acetonitrile (CAS 1000529-78-1)
- 2-(4-(Difluoromethyl)phenyl)ethan-1-amine (CAS 1000539-08-1)
- 2-(3-(Difluoromethyl)phenyl)acetic acid (CAS 1000547-15-8)
- 2-(2-(Difluoromethyl)phenyl)acetonitrile (CAS 1000556-48-8)
- 2-(2-(Difluoromethyl)phenyl)ethanamine (CAS 1000559-85-2)
Recommended Standards
- Methyl 7-(benzyloxy)benzo[d][1,3]dioxole-5-carboxylate (CAS 142531-43-9)
- (S)-3-(4-(1H-Pyrrol-1-yl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 312619-46-8)
- 6-Bromo-2-(difluoromethyl)-5-methoxypyridin-3-ol (CAS 1805370-65-3)
- 2-((2,5-Difluorobenzyl)oxy)-4-fluorobenzaldehyde (CAS 1443337-14-1)
- 2-(4-Bromophenyl)-4-(ethylthio)pyrazolo[1,5-a]pyrazine (CAS 1207007-76-8)
- 5-((6,7-Dimethoxyquinolin-4-yl)oxy)pyridin-2-amine (CAS 417722-21-5)
- Methylamine-<SUP>13</SUP>C,<SUP>15</SUP>N (CAS 1449-71-4)
- 4-amino-3-methyl-isoxazolo[4,5-c]quinoline-8-carboxylic acid (CAS 2774613-69-1)
- 8-((2-Chloroethyl)thio)-9-ethyl-9H-purine (CAS 90416-24-3)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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