5-Fluoroquinoline-8-thiol CAS 1892-91-7
| CAS No. | 1892-91-7 |
| Molecular Formula | C9H6FNS |
| Molecular Weight | 179.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluoroquinoline-8-thiol (CAS 1892-91-7) is a high-purity analytical reference standard with the molecular formula C9H6FNS and a molecular weight of 179.21 g/mol.
The molecular framework of 5-Fluoroquinoline-8-thiol (C9H6FNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6FNS |
| Molecular Weight | 179.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluoroquinoline Standards
- 6-Fluoroquinoline-2-thiol (CAS 1330753-13-3)
- 7-Fluoroquinoline-4(1H)-thione (CAS 181950-69-6)
- 8-Fluoroquinoline-2,4(1H,3H)-dione (CAS 148356-14-3)
- 8-Fluoroquinoline-2,4-diol (CAS 1823734-31-1)
- 6-Fluoroquinoline-2,4(1H,3H)-dione (CAS 2009563-91-9)
- 8-Fluoroquinoline-5,6-diamine (CAS 1092285-85-2)
- 7-Fluoroquinoline-3,4-diamine (CAS 110643-83-9)
- 8-Fluoroquinoline-3,4-diamine (CAS 110643-89-5)
Recommended Standards
- 4-(Difluoromethoxy)-3,3-dimethylpiperidine (CAS 1862539-44-3)
- (4,4-difluoro-1-methoxycyclohexyl)methanamine (CAS 1941174-37-3)
- (1R)-1-(4,4-Difluorotetrahydro-2H-pyran-2-yl)propan-1-amine (CAS 2791312-22-4)
- (4-(Difluoromethoxy)cyclohexyl)methanamine (CAS 1785032-22-5)
- 4-Methoxy-7-methylisoindoline (CAS 739365-33-4)
- N-(1-Isobutyryl-1,2,3,4-tetrahydroquinolin-7-yl)methanesulfonamide (CAS 946220-79-7)
- imidazo[1,2-a]pyridine-7-carboxylic acid hydrochloride (CAS 1423031-35-9)
- 2-Cyano-6-cyclopropoxybenzenesulfonamide (CAS 1243406-06-5)
- (Rac)-Bis-Mal-Lysine-PEG4-acid (CAS 2307731-13-9)
- 3-Amino-4,4-difluorobutanoic acid hydrochloride (CAS 78347-65-6)
- n-Acetyl-n-(prop-2-yn-1-yl)glycine (CAS 1515118-47-4)
- 8-methoxyimidazo[1,2-a]pyridine (CAS 100592-04-9)
- Tert-butyl (2-((3,4-dichlorobenzyl)amino)ethyl)carbamate (CAS 845723-26-4)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com