N-Benzyl-3,5,6-trifluoropyridin-2-amine CAS 189281-25-2
| CAS No. | 189281-25-2 |
| Molecular Formula | C12H9F3N2 |
| Molecular Weight | 238.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-Benzyl-3,5,6-trifluoropyridin-2-amine (CAS 189281-25-2) is a high-purity analytical reference standard with the molecular formula C12H9F3N2 and a molecular weight of 238.21 g/mol.
Structurally, N-Benzyl-3,5,6-trifluoropyridin-2-amine (C12H9F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 238.21 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2 |
| Molecular Weight | 238.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 2-((BENZYLOXY)CARBONYL)-1-FLUOROCYCLOPROPANECARBOXYLIC ACID (CAS 1823273-17-1)
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- 2-Ethoxy-5-phenylpyridine (CAS 136364-30-2)
- (1R,4aS,7aS)-Methyl 7-(chloromethyl)-1-methoxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (CAS 2162177-64-0)
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- 2,4,5-Trifluorobenzyl Bromide (CAS 157911-56-3)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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