2-Bromo-3-(4-fluorophenyl)propanoic acid CAS 189298-19-9
| CAS No. | 189298-19-9 |
| Molecular Formula | C9H8BrFO2 |
| Molecular Weight | 247.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-3-(4-fluorophenyl)propanoic acid (CAS 189298-19-9), molecular formula C9H8BrFO2 and molecular weight 247.06 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-3-(4-fluorophenyl)propanoic acid (C9H8BrFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-3-(4-fluorophenyl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8BrFO2 |
| Molecular Weight | 247.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F/Br-containing |
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Recommended Standards
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- 3-Bromo-2-fluoro-5-(methoxymethyl)benzaldehyde (CAS 1891083-46-7)
- (S)-2-(Bromomethyl)-5-fluoro-2,3-dihydrobenzo[b][1,4]dioxine (CAS 1932264-32-8)
- H-Met-OtBu · HCl (CAS 91183-71-0)
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- Anlotinib Impurity 4 (CAS CATO-C4X-32834)
- 6-tert-Butyl-4-hydroxy-pyran-2-one (CAS 857248-84-1)
- 4-(bromomethyl)-1-(trifluoromethyl)-1H-pyrazole (CAS 2169440-61-1)
- Dispersant NNO (CAS 9084-06-4)
- 3-Hydrazinyl-5-methyl-6-phenyl-2,5-dihydro-1,2,4-triazine (CAS 772294-58-3)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
Why CATO?
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