(R)-2,2,2-Trifluoro-1-phenylethanamine hydrochloride CAS 189350-64-9

Purity 97%+In StockPharmaceutical Standards
CAS No.189350-64-9
Molecular FormulaC8H8F3N
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-2,2,2-Trifluoro-1-phenylethanamine hydrochloride CAS 189350-64-9 chemical structure

Description

The occurrence of (R)-2,2,2-Trifluoro-1-phenylethanamine hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(R)-2,2,2-Trifluoro-1-phenylethanamine hydrochloride (CAS 189350-64-9) is a high-purity analytical reference standard with the molecular formula C8H8F3NHCl and a molecular weight of 211.61 g/mol.

(R)-2,2,2-Trifluoro-1-phenylethanamine hydrochloride (C8H8F3NHCl) contains a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-2,2,2-Trifluoro-1-phenylethanamine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H8F3N HCl
Molecular Weight211.61 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2011
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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