1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}piperazine CAS 189560-98-3

Purity 97%+In StockPharmaceutical Standards
CAS No.189560-98-3
Molecular FormulaC13H14F6N2
Molecular Weight312.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}piperazine CAS 189560-98-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}piperazine.

1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}piperazine (CAS 189560-98-3), molecular formula C13H14F6N2 and molecular weight 312.25 g/mol, is a CATO reference standard with documented purity and traceability.

1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}piperazine (C13H14F6N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H14F6N2
Molecular Weight312.25 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2011
Halogen ContentF-containing
Nitrogen Atoms2

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