2,5-Difluoro-1,4-benzenedicarbonitrile CAS 1897-49-0
| CAS No. | 1897-49-0 |
| Molecular Formula | C8H2F2N2 |
| Molecular Weight | 164.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,5-Difluoro-1,4-benzenedicarbonitrile (CAS 1897-49-0) is a high-purity analytical reference standard with the molecular formula C8H2F2N2 and a molecular weight of 164.11 g/mol.
2,5-Difluoro-1,4-benzenedicarbonitrile (C8H2F2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H2F2N2 |
| Molecular Weight | 164.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 20142-88-5 AR-1K3699 n-[2-(dimethylamino)ethyl]-1,2-benzothiazole-3-carboxamide hydrochloride(1:1) (CAS 20142-88-5)
- 2-((p-Tolyloxy)methyl)-1H-benzo[d]imidazole (CAS 3156-25-0)
- 1-Chloro-N,N',N''-triethyl-N,N',N''-trimethylsilanetriamine (CAS 1378825-94-5)
- Ethyl (3,5-dimethyl-4H-1,2,4-triazol-4-yl)carbamate (CAS 182929-48-2)
- 1-[3-(Trifluoromethyl)phenyl]cyclopentanecarbonitrile (CAS 1152590-54-9)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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