5,6,7,8-Tetrahydroquinazoline-2,4-diamine CAS 1899-40-7
| CAS No. | 1899-40-7 |
| Molecular Formula | C8H12N4 |
| Molecular Weight | 164.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5,6,7,8-Tetrahydroquinazoline-2,4-diamine (C8H12N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 5,6,7,8-Tetrahydroquinazoline-2,4-diamine (CAS 1899-40-7), a certified reference material (molecular formula C8H12N4, MW 164.21 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,6,7,8-Tetrahydroquinazoline-2,4-diamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N4 |
| Molecular Weight | 164.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
Related Tetrahydroquinazoline Standards
- 5,6,7,8-Tetrahydroquinazoline-2,6-diamine, 97% (CAS 285139-05-1)
- 5,6,7,8-Tetrahydroquinazoline-2,4,6-triamine (CAS 225504-33-6)
- 4-Methyl-5,6,7,8-tetrahydroquinazoline (CAS 103796-40-3)
- 4-Methyl-5,6,7,8-tetrahydroquinazoline-2-thiol (CAS 521305-91-9)
- 7-methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione (CAS 62484-15-5)
- 5,6,7,8-tetrahydroquinazoline-6-carboxylic acid (CAS 1369096-46-7)
- 2-Oxo-1,2,3,4-tetrahydroquinazoline-4-carboxylic acid (CAS 1378266-49-9)
- 2-Oxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid (CAS 1783725-09-6)
Recommended Standards
- 6-(Pyrrolidin-2-yl)pyridazin-3-amine (CAS 1890784-52-7)
- 4-(Piperazin-1-yl)pyridazine (CAS 194853-84-4)
- (10s,11s)-6,6,10,11-tetramethyl-4-propyl-10,11-dihydro-2h,6h,12h-dipyrano[2,3-f:2',3'-h]chromene-2,12-dione 18489-25-3 KST-1A2220 (CAS 18489-25-3)
- 2-Isopropyl-6-methyl-1H-pyrazolo[1,5-b][1,2,4]triazole (CAS 197355-54-7)
- 1,2,5,6-Tetrahydroquinolin-8-amine (CAS 136702-04-0)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 3-acetamido-3-phenylpropanoate (CAS 878108-79-3)
- 2-Aminooxazole-5-carbaldehyde (CAS 1100424-87-0)
- 2-Bromo-4-ethoxy-1-methylbenzene (CAS 1445601-62-6)
- N1-Cyclopropyl-N1-(1-(pyrazin-2-yl)ethyl)ethane-1,2-diamine (CAS 1353955-74-4)
- N-(4-Bromophenyl)-2-[4-(3-chlorophenyl)piperazin-1-yl]acetamide (CAS 329779-06-8)
- 2-(3-(Hydroxymethyl)phenyl)nicotinonitrile (CAS 1309270-49-2)
- 5-(Tert-butyl)-1-(2,4,6-trichlorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 261510-86-5)
- 4-Cyclopropoxy-5-isopropyl-2-(trifluoromethyl)pyridine (CAS 1243396-33-9)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
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