4-(Benzyloxy)-2-fluoroaniline CAS 190060-72-1
| CAS No. | 190060-72-1 |
| Molecular Formula | C13H12FNO |
| Molecular Weight | 217.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Benzyloxy)-2-fluoroaniline (CAS 190060-72-1), molecular formula C13H12FNO and molecular weight 217.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(Benzyloxy)-2-fluoroaniline is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 217.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Benzyloxy)-2-fluoroaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12FNO |
| Molecular Weight | 217.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Benzyloxy Standards
- 2-(Benzyloxy)-3-fluoroaniline (CAS 1184302-52-0)
- 3-(Benzyloxy)-5-fluoroaniline (CAS 1438272-88-8)
- 2-(Benzyloxy)-4-fluoroaniline (CAS 159471-73-5)
- 2-(Benzyloxy)-6-fluoroaniline (CAS 160564-65-8)
- 4-(Benzyloxy)-3-fluoroaniline (CAS 168268-00-6)
- 2-(Benzyloxy)-5-fluoroaniline (CAS 937596-55-9)
- 3-((Benzyloxy)methyl)-5-fluoropyridine (CAS 23586-94-9)
- 5-(Benzyloxy)-2-fluoroaniline (CAS 342042-82-4)
Recommended Standards
- 3-((2,2-Dimethylthietan-3-yl)amino)-2,3-dioxopropanoic acid (CAS 1850868-92-6)
- 2,5-Dimethoxybenzene-1-sulfonamide (CAS 19116-90-6)
- 5-cyano-3-methyl-1-benzothiophene-2-carboxylic acid (CAS 1803600-86-3)
- 1-(4-Fluorophenyl)-3-oxocyclohexanecarbonitrile (CAS 1956331-01-3)
- Propargylamine hydrochloride (CAS 15430-52-1)
- n-Methyl-4-phenyl-4h-1,2,4-triazol-3-amine hydroiodide (CAS 1423806-13-6)
- (S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester (CAS 946517-36-8)
- 1-(2,3-Dimethylphenyl)-3-(4-fluorophenyl)propan-1-one (CAS 898768-25-7)
- 5-Bromo-N,N-dimethyl-4-(piperazin-1-yl)pyridine-3-sulfonamide (CAS 1352499-52-5)
- Methyl 2,4-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1004294-98-7)
- 3-Iodo-6-methyl-2H-pyrazolo[3,4-b]pyridine (CAS 1352396-72-5)
- Diethyl (S)-(2-methylaziridin-1-yl)phosphonate (CAS 1800100-68-8)
- (5-Bromo-3-formyl-pyridin-2-yl)-carbamic acid tert-butyl ester (CAS 2352916-58-4)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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