Mirabegron Impurity 21 CAS 19008-62-9
| CAS No. | 19008-62-9 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Mirabegron Impurity 21.
As a process- or degradation-related impurity, Mirabegron Impurity 21 (CAS 19008-62-9, C8H10N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H10N2O2HCl, Mirabegron Impurity 21 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 202.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 HCl |
| Molecular Weight | 202.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Mirabegron Standards
- Mirabegron Impurity 73 (CAS 100-12-9)
- Mirabegron Impurity 40 (CAS 1154949-80-0)
- rac-Mirabegron-d5 (CAS 1215807-38-7)
- Mirabegron Impurity 147 (CAS 1310279-36-7)
- Mirabegron Impurity 32 (CAS 1310279-36-7 (free base))
- Mirabegron N-t-BOC Impurity (CAS 1329485-55-3)
- Mirabegron Impurity 139 (CAS 1330277-46-7)
- Mirabegron Impurity 62 (CAS 135365-07-0)
Recommended Standards
- Loratadine Impurity 19 (CAS CATO-C4X-142619)
- Mianserin Impurity 57 (CAS 2411967-06-9)
- Retigabine impurity 16 (CAS CATO-C4X-13156)
- 4-Methyl-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid (CAS 873450-22-7)
- (R)-2-(4-Methoxyphenyl)pyrrolidine hydrochloride (CAS 1227798-75-5)
- 1,4-Dimethyl-3-(5-methylpyridin-3-yl)-1h-pyrazol-5-amine (CAS 1492516-71-8)
- 1-Isobutyl-1h-indazol-6-amine (CAS 938523-24-1)
- 5-Bromo-1,3-dichloro-2-(4-methoxyphenoxy)benzene 55814-63-6 8150AB C13H9BrCl2O2 (CAS 55814-63-6)
- 8-(2-Nitrophenyl)-1,4-dioxa-8-azaspiro[4.5]decane (CAS 218610-20-9)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com