5-(Bromomethyl)pyrrolidin-2-one CAS 190271-85-3
| CAS No. | 190271-85-3 |
| Molecular Formula | C5H8BrNO |
| Molecular Weight | 178.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Bromomethyl)pyrrolidin-2-one.
CATO supplies 5-(Bromomethyl)pyrrolidin-2-one (CAS 190271-85-3), a certified reference material (molecular formula C5H8BrNO, MW 178.03 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Bromomethyl)pyrrolidin-2-one (C5H8BrNO) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Bromomethyl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8BrNO |
| Molecular Weight | 178.03 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- (S)-5-(Bromomethyl)pyrrolidin-2-one (CAS 72479-05-1)
- 1-(Bromomethyl)pyrrolidin-2-one (CAS 93287-12-8)
- 4-(Bromomethyl)pyrrolidin-2-one (CAS 945671-51-2)
- 5-(Bromomethyl)-3-methyl-4,5-dihydro-1,2-oxazole (CAS 68843-63-0)
- (5r)-5-(bromomethyl)pyrrolidin-2-one (R)-5-Bromomethyl-2-pyrrolidinone (r)-5-(bromomethyl)pyrrolidin-2-one 2-pyrrolidinone, 5-(bromomethyl)-, (5r)- 98612-60-3 [r,(+)]-5|A-(bromomethyl)pyrrolidine-2-one [r,(+)]-5|A-bromomethyl-2-pyrrolidone b50370 (CAS 98612-60-3)
- 2-(Bromomethyl)thiazole (CAS 131654-56-3)
- 4-(Bromomethyl)isothiazole (CAS 1378822-69-5)
- 5-(bromomethyl)thiazole hydrobromide (CAS 167998-61-0)
Recommended Standards
- n-Allyl-2-bromoacetamide (CAS 126265-30-3)
- 1-Azido-4-bromobutane (CAS 116114-55-7)
- (Z)-2-Bromo-3-(dimethylamino)acrylaldehyde (CAS 20591-60-0)
- 4-Amino-2,6-dichlorophenol (CAS 5930-28-9)
- 4,6,7-Trichloropyrido[2,3-d]pyrimidine (CAS 2820180-67-2)
- 2-Amino-6-phenylnicotinonitrile (CAS 56162-65-3)
- Methyl 2-amino-1h-indole-3-carboxylate (CAS 113772-14-8)
- 2-Butenedioic acid (2Z)-, 1-methyl ester, polymer with butyl 2-propenoate and ethenyl acetate, ammonium sodium salt (CAS 71808-72-5)
- n-(3-Chloroquinoxalin-2-yl)-2,5-difluorobenzene-1-sulfonamide (CAS 735322-75-5)
- (2R,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid (CAS 200184-87-8)
- tert-Butyl (2-(2-chloro-6-formylpyridin-4-yl)ethyl)carbamate (CAS 1393531-41-3)
- 2-(4-Methylpiperazin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 154816-49-6)
- Isopropyl 4-oxo-2-azetidinecarboxylate (CAS 1354349-40-8)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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