5-(Pyridin-2-yl)thiophene-2-sulfonamide CAS 190659-63-3

Purity 97%+In StockPharmaceutical Standards
CAS No.190659-63-3
Molecular FormulaC9H8N2O2S2
Molecular Weight240.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(Pyridin-2-yl)thiophene-2-sulfonamide CAS 190659-63-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-(Pyridin-2-yl)thiophene-2-sulfonamide (CAS 190659-63-3), molecular formula C9H8N2O2S2 and molecular weight 240.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(Pyridin-2-yl)thiophene-2-sulfonamide (C9H8N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H8N2O2S2
Molecular Weight240.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2011
Nitrogen Atoms2
Sulfur Atoms2

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Why CATO?