6-(2,2,2-TRifluoro-acetylamino)-nicotinic acid methyl ester CAS 1906808-06-7
| CAS No. | 1906808-06-7 |
| Molecular Formula | C9H7F3N2O3 |
| Molecular Weight | 248.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(2,2,2-TRifluoro-acetylamino)-nicotinic acid methyl ester.
CATO supplies 6-(2,2,2-TRifluoro-acetylamino)-nicotinic acid methyl ester (CAS 1906808-06-7), a certified reference material (molecular formula C9H7F3N2O3, MW 248.16 g/mol) for analytical method development and quality control.
6-(2,2,2-TRifluoro-acetylamino)-nicotinic acid methyl ester (C9H7F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(2,2,2-TRifluoro-acetylamino)-nicotinic acid methyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7F3N2O3 |
| Molecular Weight | 248.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- (1E)-2,2,2-trifluoro-1-[(1S,4R)-4,7,7-trimethyl-3-oxo-2-bicyclo[2.2.1]heptanylidene]ethanolate (1E)-2,2,2-tris(fluoranyl)-1-[(1S,4R)-4,7,7-trimethyl-3-oxidanylidene-2-bicyclo[2.2.1]heptanylidene]ethanolate 51800-98-7 A828784 (CAS 51800-98-7)
- 2,2,2-Trifluoro-1-(4-(propylthio)phenyl)ethan-1-one (CAS 1443343-29-0)
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Recommended Standards
- 3-Nitro-2-(trifluoromethyl)acetanilide (CAS 1807058-35-0)
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- 2-(Carboxymethyl)-5-(Trifluoromethyl)Benzoic Acid (CAS 207804-91-9)
- 2-(1-Methyl-1h-imidazole-4-sulfonamido)acetic acid (CAS 1249411-93-5)
- 5-Bromo-N-((tetrahydrothiophen-2-yl)methyl)thiophene-2-carboxamide (CAS 1424040-00-5)
- N-benzyl-2-(2-fluorophenoxy)ethan-1-amine hydrochloride (CAS 1609409-32-6)
- cis-(1s,4s)-4-((Tert-butyldimethylsilyl)oxy)cyclohexan-1-ol (CAS 103202-62-6)
- 2,2'-(((Benzyloxy)carbonyl)azanediyl)diacetic acid (CAS 17335-88-5)
- 6-(2-Fluoro-5-methoxycarbonylphenyl)-2-formylphenol (CAS 1261919-29-2)
- ({4-chloropyrrolo[2,1-f][1,2,4]triazin-7-yl}methyl)(methyl)amine (CAS 1556553-32-2)
- n-Isopropyl-4-phenoxybutan-1-amine (CAS 1226010-35-0)
- 4-(2-Fluoro-4-methoxyphenyl)thiazol-2-amine (CAS 718596-15-7)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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