2-Bromo-4,6-difluorophenyl isocyanate CAS 190774-48-2
| CAS No. | 190774-48-2 |
| Molecular Formula | C7H2BrF2NO |
| Molecular Weight | 234.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Bromo-4,6-difluorophenyl isocyanate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 234.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Bromo-4,6-difluorophenyl isocyanate (CAS 190774-48-2) is a high-purity analytical reference standard with the molecular formula C7H2BrF2NO and a molecular weight of 234.00 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4,6-difluorophenyl isocyanate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2BrF2NO |
| Molecular Weight | 234.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-4,6-dihydroxynicotinic acid (CAS 1216835-16-3)
- 6-Bromo-4,5-difluoro-3H-1,2,3-benzotriazole (CAS 1381944-47-3)
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- 4-Bromo-2,6-Difluorophenyl Isocyanate (CAS 302912-26-1)
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Recommended Standards
- 5,7-Dichloro-4-nitro-2,1,3-benzoxadiazole (CAS 15944-78-2)
- 2-Iodo-1,4-benzoquinone (CAS 3958-83-6)
- 3-Iodopyrazine-2-carbaldehyde (CAS 212471-35-7)
- 6-Bromo-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid (CAS 2147483-69-8)
- 4-(3-Pyrrolidinylmethyl)morpholine dihydrochloride (CAS 1220033-16-8)
- 3-Methoxy-5-methyl-2-phenylimidazo[1,2-a]pyridine (CAS 89192-99-4)
- Methyl 2,6-difluorobenzoate (CAS 13671-00-6)
- 5-Chloro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 75993-42-9)
- 3-[(3-Bromobenzyl)oxy]benzaldehyde (CAS 137489-76-0)
- 3-((3-Methylbenzyl)thio)-6-(pyridin-3-yl)pyridazine (CAS 893993-72-1)
- N-(Pyrrolidin-2-ylidene)aminosulfonamide (CAS 716364-40-8)
- 9-(Bis(benzylthio)methylene)-10-phenyl-9,10-dihydroacridine (CAS 555152-96-0)
- 2-(2-Quinoxalinylthio)acetic Acid (CAS 69001-90-7)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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