rac-(2R,3S)-1-methyl-2-phenylpyrrolidine-3-carboxylic acid hydrochloride CAS 1909288-19-2
| CAS No. | 1909288-19-2 |
| Molecular Formula | C12H15NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 241.72 g/mol gives rac-(2R,3S)-1-methyl-2-phenylpyrrolidine-3-carboxylic acid hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
rac-(2R,3S)-1-methyl-2-phenylpyrrolidine-3-carboxylic acid hydrochloride (CAS 1909288-19-2), molecular formula C12H15NO2HCl and molecular weight 241.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of rac-(2R,3S)-1-methyl-2-phenylpyrrolidine-3-carboxylic acid hydrochloride (C12H15NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15NO2 HCl |
| Molecular Weight | 241.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2-Chlorophenyl)(pyrrolidin-1-yl)methanone (CAS 70657-66-8)
- 2,5-Dioxopyrrolidin-1-yl dodecanoate (CAS 14565-47-0)
- 1-Methylisoquinolin-7-ol (CAS 31181-23-4)
- 1-(1-Phenyl-1H-pyrazol-3-yl)ethan-1-amine (CAS 1592280-18-6)
- 1-(3,4-dichloro-2-hydroxyphenyl)propan-1-one (CAS 777067-72-8)
- 2-Chloro-4-(difluoromethyl)-3-methoxy-6-methylpyridine (CAS 1805410-43-8)
- 2-[(2,6-Dichlorophenyl)sulfanyl]-N-[2-(phenylsulfanyl)ethyl]acetamide (CAS 337923-41-8)
- 1-(2-Chloroacetyl)-4,5-dihydro-1h-pyrazole-5-carbonitrile (CAS 761414-68-0)
- 3-(5-(Trifluoromethyl)furan-2-yl)acrylic acid (CAS 65865-29-4)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com