tert-butyl (2S)-2-(2-chloroacetamido)-4-methylpentanoate CAS 1909294-05-8
| CAS No. | 1909294-05-8 |
| Molecular Formula | C12H22ClNO3 |
| Molecular Weight | 263.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies tert-butyl (2S)-2-(2-chloroacetamido)-4-methylpentanoate (CAS 1909294-05-8), a certified reference material (molecular formula C12H22ClNO3, MW 263.76 g/mol) for analytical method development and quality control.
The molecular framework of tert-butyl (2S)-2-(2-chloroacetamido)-4-methylpentanoate (C12H22ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-butyl (2S)-2-(2-chloroacetamido)-4-methylpentanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H22ClNO3 |
| Molecular Weight | 263.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-butyl (2R)-2-(2-chloroacetamido)-4-methylpentanoate (CAS 1909288-17-0)
- 2-Chloro-1-(2,2,4,6-tetramethyl-2H-quinolin-1-yl)-ethanone (CAS 364383-62-0)
- tert-Butyl ((3S,4S)-1-chloro-4-methyl-2-oxohexan-3-yl)carbamate (CAS 161805-78-3)
- 2-Chloro-1-(2,2,4,7-tetramethylquinolin-1(2H)-yl)ethan-1-one (CAS 28745-09-7)
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