4-(4-hydroxypiperidin-1-yl)pyridine-2-carboxylic acid hydrochloride CAS 1909326-42-6
| CAS No. | 1909326-42-6 |
| Molecular Formula | C11H14N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-hydroxypiperidin-1-yl)pyridine-2-carboxylic acid hydrochloride (CAS 1909326-42-6) is a high-purity analytical reference standard with the molecular formula C11H14N2O3HCl and a molecular weight of 258.70 g/mol.
The molecular framework of 4-(4-hydroxypiperidin-1-yl)pyridine-2-carboxylic acid hydrochloride (C11H14N2O3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O3 HCl |
| Molecular Weight | 258.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related hydroxypiperidin Standards
- 2-[2-(4-Hydroxypiperidin-1-yl)-ethyl]isoindole-1,3-dione (CAS 101620-61-5)
- 4-[(4-hydroxypiperidin-1-yl)sulfonyl]benzoic acid (CAS 1016503-99-3)
- 4-[(4-hydroxypiperidin-1-yl)sulfonyl]benzonitrile (CAS 1016887-02-7)
- 6-(4-Hydroxypiperidin-1-yl)nicotinonitrile (CAS 1017034-18-2)
- 2-(4-Hydroxypiperidin-1-yl)-2-phenylacetonitrile (CAS 1018437-11-0)
- 5-Ethyl-4-hydroxypiperidin-2-one (CAS 102014-75-5)
- (R)-5-Hydroxypiperidin-2-one (CAS 102774-92-5)
- 2-(4-Hydroxypiperidin-1-yl)-N-(1-(thiophen-2-yl)ethyl)acetamide (CAS 1030765-44-6)
Recommended Standards
- Methyl 4-amino-3-(3-methoxyphenyl)butanoate (CAS 1263211-17-1)
- (4-Ethoxy-3-methylpyridin-2-yl)methyl acetate (CAS 1025888-85-0)
- 1-Methyl-1,4,9-triazaspiro[5.5]Undecan-5-one (CAS 1268334-95-7)
- 3-[4-(Propan-2-yl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 886967-70-0)
- Alogliptin Impurity 92 (CAS CATO-C4X-109992)
- 1,3-Isobenzofurandione, 4,5,6,7-tetrabromo-, polymer with 1,2-ethanediol and 2,5-furandione (CAS 65682-26-0)
- n-(3-Fluorophenyl)-2-phenoxyacetamide (CAS 303989-18-6)
- (1-(Methylsulfonyl)-1H-benzo[d]imidazol-2-yl)methanol (CAS 43215-15-2)
- 2-Methoxy-4-(3-trifluoromethylphenyl)benzoic acid (CAS 1237117-50-8)
- Glucagon Monohydrochloride (CAS 28270-04-4)
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