1-(4,6-Dimethoxypyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea CAS 190954-81-5
| CAS No. | 190954-81-5 |
| Molecular Formula | C14H13F3N4O3 |
| Molecular Weight | 342.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-(4,6-Dimethoxypyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 190954-81-5), a certified reference material (molecular formula C14H13F3N4O3, MW 342.27 g/mol) for analytical method development and quality control.
1-(4,6-Dimethoxypyrimidin-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (C14H13F3N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13F3N4O3 |
| Molecular Weight | 342.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Dimethoxypyrimidin Standards
- 1-(4,6-Dimethoxypyrimidin-2-yl)-1-(3-(trifluoromethyl)pyridin-2-yl)urea (CAS 178403-35-5)
- 2-((4,6-Dimethoxypyrimidin-2-yl)oxy)-6-(1-(methoxyimino)ethyl)benzoic acid (CAS 136191-56-5)
- (E)-({3-[(4,6-dimethoxypyrimidin-2-yl)oxy]-4-methoxyphenyl}methylidene)(ethoxy)amine (CAS 866154-93-0)
- 1-(2,4-Dimethoxypyrimidin-5-yl)-3-(naphthalen-2-yl)urea (CAS 1448028-45-2)
- Methyl 2-((4,6-dimethoxypyrimidin-2-yl)oxy)-6-(1-(methoxyimino)ethyl)benzoate (CAS 136191-64-5)
- 4-(2,6-Dimethoxypyrimidin-4-yl)-N-(4-fluorophenyl)piperazine-1-carboxamide (CAS 1021214-70-9)
- (E)-3-((4,6-dimethoxypyrimidin-2-yl)oxy)-4-methoxybenzaldehyde O-methyl oxime (CAS 866154-94-1)
- 4-((4,6-Dimethoxypyrimidin-2-yl)oxy)-2-(methylsulfonyl)benzofuran-3-ol (CAS 143436-10-6)
Recommended Standards
- N-(6-Amino-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-(4-(trifluoromethyl)phenyl)acetamide (CAS 167299-45-8)
- (2E)-2-Cyano-3-(dimethylamino)-N'-[(1E)-4,4,4-trifluoro-1-(furan-2-yl)-3-oxobutylidene]prop-2-enehydrazide (CAS 478078-13-6)
- N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide (CAS 149981-35-1)
- (4-bromo-5-cyano-2-naphthyl) 2,2-dimethylpropanoate (CAS 2757096-98-1)
- 2-Methylcyclopentanol (CAS 24070-77-7)
- 6'-Bromospiro[cyclopropane-1,1'-inden]-3'(2'H)-one (CAS 1396777-69-7)
- 2-(Cyclohexyloxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1310383-05-1)
- Ethyl 2-(2-chloroethyl)piperidine-1-carboxylate (CAS 865076-02-4)
- 1-(4-Isopropylbenzyl)piperidine-4-carboxylic acid hydrochloride (CAS 1185298-68-3)
- Ethyl 4-amino-1-methyl-6-oxo-2,6-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 66857-98-5)
- N-(hexan-2-yl)cyclopentanamine (CAS 1157145-94-2)
- 2-(3,4-Dichlorophenyl)-5,6-dimethyl-1H-benzo[d]imidazole (CAS 1175697-01-4)
- tert-Butyl 3-(((benzyloxy)carbonyl)amino)pyrrolidine-1-carboxylate (CAS 325775-36-8)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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