2-((5-Amino-6-chloropyrimidin-4-yl)thio)acetonitrile CAS 19144-84-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-Amino-6-chloropyrimidin-4-yl)thio)acetonitrile.

2-((5-Amino-6-chloropyrimidin-4-yl)thio)acetonitrile (CAS 19144-84-4), molecular formula C6H5ClN4S and molecular weight 200.65 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-((5-Amino-6-chloropyrimidin-4-yl)thio)acetonitrile (C6H5ClN4S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-((5-Amino-6-chloropyrimidin-4-yl)thio)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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