(R)-1-benzyl-3,3-difluoro-4-hydroxypyrrolidin-2-one CAS 1914929-31-9
| CAS No. | 1914929-31-9 |
| Molecular Formula | C11H11F2NO2 |
| Molecular Weight | 227.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-1-benzyl-3,3-difluoro-4-hydroxypyrrolidin-2-one (CAS 1914929-31-9) is a high-purity analytical reference standard with the molecular formula C11H11F2NO2 and a molecular weight of 227.21 g/mol.
Structurally, (R)-1-benzyl-3,3-difluoro-4-hydroxypyrrolidin-2-one (C11H11F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 227.21 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (R)-1-benzyl-3,3-difluoro-4-hydroxypyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11F2NO2 |
| Molecular Weight | 227.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Ethoxy-1,3-dimethoxy-5-nitrobenzene (CAS 189564-60-1)
- 6-Amino-2,3,4-trimethoxybenzoic acid (CAS 1967-88-0)
- 5-b-D-Ribofuranosyl-2(1H)-pyridinone (CAS 188871-50-3)
- (2,3-Difluorophenyl)(morpholino)methanone (CAS 351038-43-2)
- 6-[(tert-butoxy)carbonyl]-5h,6h,7h-pyrrolo[3,4-b]pyridine-3-carboxylicacid (CAS 1618083-75-2)
- 2-Fluoro-5-(methoxymethoxy)phenol (CAS 1881331-51-6)
- 2-Amino-4-(3-fluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 107752-98-7)
- N-(2,4-Difluorophenyl)-4-(2,5-dioxopyrrolidin-1-yl)benzamide (CAS 330200-90-3)
- 7-AVCA Impurity 4 (CAS CATO-C4X-23164)
- 1-(4-Bromobutoxy)-3-methylbenzene (CAS 81368-22-1)
- 4-(2-Benzylidenehydrazinyl)-2-(isopropylthio)-6-methylpyrimidine (CAS 154496-67-0)
- (S)-2-((S)-1-((S)-2-Amino-3-phenylpropanoyl)pyrrolidine-2-carboxamido)propanoic acid (CAS 81391-38-0)
- Antide Acetate (CAS 625092-10-6)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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