2-Chloro-7-methoxy-N-phenylquinazolin-4-amine CAS 192218-48-7
| CAS No. | 192218-48-7 |
| Molecular Formula | C15H12ClN3O |
| Molecular Weight | 285.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-7-methoxy-N-phenylquinazolin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-7-methoxy-N-phenylquinazolin-4-amine (CAS 192218-48-7), molecular formula C15H12ClN3O and molecular weight 285.73 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C15H12ClN3O, 2-Chloro-7-methoxy-N-phenylquinazolin-4-amine contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 285.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H12ClN3O |
| Molecular Weight | 285.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-Chloro-N-(2-cyanoethyl)-N-phenylnicotinamide (CAS 1019354-92-7)
- 1-(5-Chloro-1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidine-4-carboxylic acid (CAS 1082393-19-8)
- 2-Chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)benzamide (CAS 1377965-22-4)
- Methyl 2-chloro-4-(((1r,4r)-4-hydroxycyclohexyl)-amino)pyrimidine-5-carboxylate (CAS 1497419-93-8)
- 1-(5-Chloro-1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidine-3-carboxylic acid (CAS 1708428-00-5)
- 2-Chloro-N-(4-methoxyphenyl)quinazolin-4-amine (CAS 192217-99-5)
- 2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine (CAS 7597-22-0)
- 2-Chloro-N-(2-(1-methyl-1H-pyrazol-3-yl)phenyl)pyrimidin-4-amine (CAS 2135586-31-9)
Recommended Standards
- (1-(3-Chlorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol (CAS 618383-41-8)
- 5-(2-Chloropyridin-3-yl)-3-(3,4-dimethylphenyl)-1,2,4-oxadiazole (CAS 1774901-00-6)
- 2-(2-Amino-5-chlorophenyl)-4-methylphthalazin-1(2H)-one (CAS 296770-22-4)
- 1-(2-(4-Chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidin-6-yl)ethan-1-one (CAS 175201-63-5)
- tert-Butyl 4-Amino-2-methoxybenzoate (CAS 1215074-48-8)
- 1-Benzyl-3-(4-ethylphenyl)-1h-pyrazole-4-carboxylic acid (CAS 956386-81-5)
- 4-([1,1'-biphenyl]-4-yl)butan-2-amine (CAS 859283-60-6)
- Bicalutamide Impurity 40 (CAS CATO-C4X-101340)
- 4-Nitrophenyl 2-acetamido-2-deoxy-4-6-O-p-methoxybenzylidene-α-D-galactopyranoside (CAS 59868-86-9)
- (R)-2-(5-Ethylthiophen-2-yl)propan-1-ol (CAS 2762829-20-7)
- Methyl 2-(3-phenyl-1H-1,2,4-triazol-1-yl)acetate (CAS 1416344-83-6)
- 2,6-Dichloro-7-methoxyquinazolin-4-amine (CAS 79025-77-7)
- 2-[4-(pyridin-2-yl)piperazin-1-yl]propanoic acid (CAS 938248-23-8)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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