2-(2-Chlorophenyl)imidazo[1,2-a]pyrimidine-3-carboxylic acid CAS 1923069-07-1
| CAS No. | 1923069-07-1 |
| Molecular Formula | C13H8ClN3O2 |
| Molecular Weight | 273.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chlorophenyl)imidazo[1,2-a]pyrimidine-3-carboxylic acid.
2-(2-Chlorophenyl)imidazo[1,2-a]pyrimidine-3-carboxylic acid (CAS 1923069-07-1) is a high-purity analytical reference standard with the molecular formula C13H8ClN3O2 and a molecular weight of 273.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(2-Chlorophenyl)imidazo[1,2-a]pyrimidine-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-Chlorophenyl)imidazo[1,2-a]pyrimidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8ClN3O2 |
| Molecular Weight | 273.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 2-(4-Chlorophenyl)-4-(furan-2-ylmethylene)oxazol-5(4H)-one (CAS 111865-34-0)
- 5-(3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-ol (CAS 1223889-44-8)
- 1-(4-Chlorophenyl)-3-nitro-1H-pyrrolo[2,3-c]pyridine (CAS 1334713-80-2)
- 3-(4-Chlorophenyl)-5-nitro-1H-indazole (CAS 1346808-74-9)
- 5-[3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-1,2-dihydropyridin-2-one (CAS 1400540-72-8)
- 2-(4-Chlorophenyl)-6-nitro-1H-1,3-benzodiazole (CAS 1571-87-5)
- 2-(3-Chlorophenyl)-5-nitro-1H-benzo[d]imidazole (CAS 1571-88-6)
- 2-(2-Chlorophenyl)-5-nitro-1H-benzo[d]imidazole (CAS 1571-89-7)
Recommended Standards
- Tert-butyl (5-chloro-3-nitropyridin-2-yl)carbamate (CAS 1824477-72-6)
- 2-(2-Chlorophenyl)imidazo[1,2-b]pyridazine-3-carboxylic acid (CAS 1956331-42-2)
- tert-butyl N-(2-chloro-3-nitropyridin-4-yl)carbamate (CAS 1803598-41-5)
- 2-(2-Chlorophenyl)imidazo[1,2-a]pyrazine-3-carboxylic acid (CAS 1956371-67-7)
- 1-(Bis(trimethylsilyl)methyl)-1H-benzo[d][1,2,3]triazole (CAS 122296-01-9)
- (4-(Aminomethyl)piperidin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone hydrochloride (CAS 1353962-72-7)
- 2,4-Difluoro-N-(quinolin-8-yl)benzenesulfonamide (CAS 931593-20-3)
- 2,4-Dimethylphenylboronic Acid (CAS 55499-44-0)
- 4,5-Dibromo-2-phenyloxazole (CAS 92629-12-4)
- Fluroxypyr-1-Methylheptylester (CAS 81406-37-3)
- (E)-4-Hydroxynon-2-en-8-ynal (CAS 1011268-23-7)
- 4-Formyl-2,6-dimethylbenzoic Acid (CAS 306296-76-4)
- Tert-butyl (3-aminopropyl)(tetrahydro-2H-pyran-4-yl)carbamate (CAS 1305712-80-4)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
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