5-(4-Fluorophenyl)-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one CAS 1923190-14-0
| CAS No. | 1923190-14-0 |
| Molecular Formula | C18H10FNO3 |
| Molecular Weight | 307.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Fluorophenyl)-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one.
5-(4-Fluorophenyl)-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one (CAS 1923190-14-0), molecular formula C18H10FNO3 and molecular weight 307.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(4-Fluorophenyl)-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one (C18H10FNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10FNO3 |
| Molecular Weight | 307.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 2-((3-Fluorophenyl)ethynyl)-4-hydroxy-5-phenyl-6H-1,3-oxazin-6-one (CAS 1956324-52-9)
- 5-(3-Fluorophenyl)-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one (CAS 1956324-70-1)
- 5-(2-Fluorophenyl)-4-hydroxy-2-(phenylethynyl)-6H-1,3-oxazin-6-one (CAS 1956370-01-6)
- 2-((2-Fluorophenyl)ethynyl)-4-hydroxy-5-phenyl-6H-1,3-oxazin-6-one (CAS 1956377-05-1)
- 2-((4-Fluorophenyl)ethynyl)-4-hydroxy-5-phenyl-6H-1,3-oxazin-6-one (CAS 1956385-72-0)
- 5-(3-Fluorophenyl)-7-(pyridin-4-yloxy)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 921627-84-1)
- 5-(4-Fluorophenyl)-7-(pyridin-4-yloxy)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 921627-85-2)
- Ethyl 1-[2-(4-fluorophenyl)ethyl]-2,4-dioxopiperidine-3-carboxylate (CAS 1400636-78-3)
Recommended Standards
- 2-(Diphenylphosphino)nicotinic acid (CAS 171562-73-5)
- 3-Formylphenyl 3-nitrobenzenesulfonate (CAS 1432437-14-3)
- 4-Formylphenyl 3-nitrobenzenesulfonate (CAS 1334304-62-9)
- 2-Formylphenyl 4-nitrobenzenesulfonate (CAS 116748-53-9)
- 6-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one (CAS 5399-91-7)
- 4-Methoxy-3-nitropyridine hydrate (CAS 1881293-28-2)
- 3-(Hydroxymethyl)-3-azetidinecarboxylic acid (CAS 102562-26-5)
- 2-Bomoquinazolin-4-amine (CAS 1264036-99-8)
- N-(4-chlorobenzyl)oxetan-3-amine (CAS 1340248-48-7)
- Ethyl 3-(6-methoxynaphthalen-2-yl)-3-oxopropanoate (CAS 62550-56-5)
- 2-Methoxy-1-(4-(trifluoromethyl)phenyl)ethanol (CAS 306298-23-7)
- 2-Methyl-1H-benzimidazol-5-ol hydrobromide (CAS 1417568-15-0)
- (2-((Tetrahydro-2H-thiopyran-4-yl)amino)phenyl)methanol (CAS 1157519-56-6)
- Hippocampal Cholinergic Neurostimulating Peptide (CAS 140158-49-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com