1-[3-bromo-4-(trifluoromethoxy)phenyl]hexahydropyrimidine-2,4-dione CAS 1925551-42-3
| CAS No. | 1925551-42-3 |
| Molecular Formula | C11H8BrF3N2O3 |
| Molecular Weight | 353.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-[3-bromo-4-(trifluoromethoxy)phenyl]hexahydropyrimidine-2,4-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-[3-bromo-4-(trifluoromethoxy)phenyl]hexahydropyrimidine-2,4-dione (CAS 1925551-42-3) is a high-purity analytical reference standard with the molecular formula C11H8BrF3N2O3 and a molecular weight of 353.09 g/mol.
The molecular framework of 1-[3-bromo-4-(trifluoromethoxy)phenyl]hexahydropyrimidine-2,4-dione (C11H8BrF3N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8BrF3N2O3 |
| Molecular Weight | 353.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
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Recommended Standards
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- 2-(4-Bromophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244086-94-8)
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- Mirtazapine (CAS 85650-52-8)
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- 5-Ethynyl-1,3-difluoro-2-methoxybenzene (CAS 1421340-96-6)
- Phosphoric Acid Dioctyl Ester Sodium Salt (CAS 1560-42-5)
- Peptide 440 (CAS CATO-CPTD788440)
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