Migalastat Impurity 2 CAS 1932484-87-1

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.1932484-87-1
Molecular FormulaC6H12N2O5
Molecular Weight192.17 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Migalastat Impurity 2 CAS 1932484-87-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 192.17 g/mol gives Migalastat Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Migalastat Impurity 2 (CAS 1932484-87-1, C6H12N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Migalastat Impurity 2 (C6H12N2O5) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H12N2O5
Molecular Weight192.17 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1996
Nitrogen Atoms2

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