2-Chloropyrido[4,3-d]pyrimidin-4-amine CAS 1935150-89-2
| CAS No. | 1935150-89-2 |
| Molecular Formula | C7H5ClN4 |
| Molecular Weight | 180.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloropyrido[4,3-d]pyrimidin-4-amine.
CATO supplies 2-Chloropyrido[4,3-d]pyrimidin-4-amine (CAS 1935150-89-2), a certified reference material (molecular formula C7H5ClN4, MW 180.59 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloropyrido[4,3-d]pyrimidin-4-amine (C7H5ClN4) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN4 |
| Molecular Weight | 180.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloropyrido Standards
- 6-chloropyrido[3,2-d]pyrimidin-4-amine (CAS 1499166-63-0)
- 1-Chloropyrido[3,4-d]pyridazin-4-amine (CAS 2730140-57-3)
- 3-Chloropyrido[2,3-b]pyrazin-6-amine (CAS 936760-62-2)
- 3-Chloropyrido[3,4-b]pyrazin-5-amine (CAS 2089381-31-5)
- 6-Chloropyrido[2,3-d]pyrimidin-2-amine (CAS 882679-26-7)
- 7-Chloropyrido[3,4-b]pyrazin-5-amine (CAS 2304630-97-3)
- 6-Chloropyrido[2,3-b]pyrazin-3(4H)-one (CAS 1350925-21-1)
- 2-Chloropyrido[4,3-d]pyrimidin-5(6H)-one (CAS 1393570-12-1)
Recommended Standards
- 4-Chloro-1H-pyrrolo[2,3-c]pyridine-3-carbaldehyde (CAS 1935055-27-8)
- 1-(4-Chlorophenyl)-1h-1,2,3,4-tetrazole (CAS 25108-32-1)
- 7-Chloro-2H-chromen-2-one (CAS 19063-54-8)
- 2-Chloro-5-(pyridin-4-yl)oxazole (CAS 1896654-86-6)
- 2-Chloro-3-(difluoromethyl)-6-iodoisonicotinaldehyde (CAS 1805359-02-7)
- [2-(6-Amino-9H-purin-9-yl)]ethanol-d4 (CAS 1216900-94-5)
- Methyl 4-bromo-2-fluoro-3-methylbenzoate (CAS 1206680-27-4)
- tert-Butyl (2-(allylamino)-2-oxoethyl)carbamate (CAS 847549-99-9)
- N,N'-Bis(salicylidene)-o-phenylenediamine Vanadium(IV) oxide complex (CAS 32065-17-1)
- 2-(Chloromethyl)-1-ethyl-1H-imidazole hydrochloride (CAS 135206-88-1)
- 4-Hydroxypicolinic Acid Hydrobromide (CAS 125545-96-2)
- 3,4-Diamino-5-methylpyridine (CAS 13958-86-6)
- 4-[3,5-bis(trifluoromethyl)phenyl]-3-chloro-2-butanone (CAS 439094-40-3)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com