tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate CAS 1935172-10-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1935172-10-3
Molecular FormulaC13H12BrFINO2
Molecular Weight440.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate CAS 1935172-10-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 440.05 g/mol gives tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate (CAS 1935172-10-3) is a high-purity analytical reference standard with the molecular formula C13H12BrFINO2 and a molecular weight of 440.05 g/mol.

tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate (C13H12BrFINO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl 7-bromo-4-fluoro-3-iodo-1H-indole-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H12BrFINO2
Molecular Weight440.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1996
Halogen ContentF/Br/I-containing
Nitrogen Atoms1

Recommended Standards

Why CATO?