3-(3-chloropyridin-4-yl)-1,2,4-thiadiazol-5-amine CAS 1935264-14-4
| CAS No. | 1935264-14-4 |
| Molecular Formula | C7H5ClN4S |
| Molecular Weight | 212.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(3-chloropyridin-4-yl)-1,2,4-thiadiazol-5-amine (C7H5ClN4S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-(3-chloropyridin-4-yl)-1,2,4-thiadiazol-5-amine (CAS 1935264-14-4) is a high-purity analytical reference standard with the molecular formula C7H5ClN4S and a molecular weight of 212.66 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(3-chloropyridin-4-yl)-1,2,4-thiadiazol-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN4S |
| Molecular Weight | 212.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related chloropyridin Standards
- 3-(3-Chloropyridin-2-yl)-1,2,4-thiadiazol-5-amine (CAS 1179362-16-3)
- 3-(2-chloropyridin-3-yl)-1,2,4-thiadiazol-5-amine (CAS 1909325-80-9)
- 5-(2-Chloropyridin-4-yl)-1,3,4-thiadiazol-2-amine (CAS 474327-26-9)
- 1-(6-Chloropyridin-2-yl)piperidin-4-ol (CAS 1220036-23-6)
- 4-((2-Chloropyridin-3-yl)methyl)morpholine (CAS 1250205-26-5)
- 1-((6-Chloropyridin-3-yl)methyl)pyrrolidin-3-ol (CAS 1343606-51-8)
- 3-((3-Chloropyridin-4-yl)methyl)pyrrolidin-3-ol (CAS 1479230-02-8)
- N-(4-chloropyridin-2-yl)pivalamide (CAS 188577-70-0)
Recommended Standards
- 3-(4-Chlorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 192817-66-6)
- N-hydroxybenzo[d]thiazole-6-carbimidoyl chloride (CAS 1956426-73-5)
- 1-(3-Chlorophenyl)-1H-tetrazole-5-thiol (CAS 22384-88-9)
- 8-Chloro-2-(methylthio)pyrimido[5,4-d]pyrimidine (CAS 176637-10-8)
- Cesium hexafluorophosphate(V) (CAS 16893-41-7)
- 4-Cyclopropoxy-5-fluoro-2-(methylthio)pyridine (CAS 1243403-50-0)
- L-Asparagine Monohydrate (CAS 5794-13-8)
- 2,4-Difluoro-5-nitromandelic acid (CAS 1803787-26-9)
- (E)-2,4-dimethylpent-2-enoic acid (CAS 3876-52-6)
- Risdiplam Impurity 1 (CAS CATO-C4X-30121)
- tert-butyl N-[1-(3,3,3-trifluoropropanoyl)piperidin-4-yl]carbamate (CAS 1240528-25-9)
- 2-Acetamido-N1-(4-fluorophenyl)-N3-(4-methoxyphenyl)malonamide (CAS 866018-01-1)
- 2-Fluoro-4-methoxybenzyl alcohol (CAS 405-09-4)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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