6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile CAS 1935287-10-7
| CAS No. | 1935287-10-7 |
| Molecular Formula | C7H11ClN4 |
| Molecular Weight | 186.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile (CAS 1935287-10-7) is a high-purity analytical reference standard with the molecular formula C7H11ClN4 and a molecular weight of 186.64 g/mol.
Owing to a nitrile group, chlorine substitution, an aromatic ring system, 6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11ClN4 |
| Molecular Weight | 186.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 1-(4-Chloro-3,5-dimethyl-1h-pyrazol-1-yl)propan-2-one (CAS 1001465-98-0)
- 2-Chloro-6-(2-methylpropoxy)pyrazine (CAS 1016508-48-7)
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Recommended Standards
- 4-chloro-1h-pyrazolo[4,3-c]pyridine-3-carbonitrile (CAS 1934605-77-2)
- 4-chloro-1h-pyrazolo[3,4-b]pyridine-3-carbonitrile (CAS 1936189-92-2)
- 2-(4-Chloro-2-methoxyphenyl)ethan-1-ol (CAS 193290-24-3)
- 6-Chloro-N4-propylpyrimidine-4,5-diamine (CAS 195252-56-3)
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