3-Iodo-1H-pyrazolo[3,4-b]pyrazine-5-carbonitrile CAS 1936029-98-9
| CAS No. | 1936029-98-9 |
| Molecular Formula | C6H2IN5 |
| Molecular Weight | 271.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Iodo-1H-pyrazolo[3,4-b]pyrazine-5-carbonitrile (CAS 1936029-98-9) is a high-purity analytical reference standard with the molecular formula C6H2IN5 and a molecular weight of 271.02 g/mol.
The molecular framework of 3-Iodo-1H-pyrazolo[3,4-b]pyrazine-5-carbonitrile (C6H2IN5) is characterized by a nitrile group, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H2IN5 |
| Molecular Weight | 271.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- 2-Bromo-5-cyano-4-nitrobenzoic acid (CAS 1807029-44-2)
- 5,6-Dichloro-2-(Trifluoromethyl)-1H-Benzimidazol-4-Ol (CAS 19690-31-4)
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- 5-Bromo-6-nitroisoindoline-1,3-dione (CAS 64823-14-9)
- (2-Chloro-4-fluorophenyl)(3-hydroxyazetidin-1-yl)methanone (CAS 1343974-68-4)
- (S)-6-(tert-butoxymethyl)-2-oxa-5,8-diazaspiro[3.5]Nonan-7-one (CAS 2091614-61-6)
- (Thiazol-5-ylmethyl)glycine (CAS 1339037-95-4)
- 2-Bromo-3-methoxy-1-methyl-4-nitrobenzene (CAS 1807185-87-0)
- 2,4-Dibromo-6-fluoro-3-iodotoluene (CAS 1000576-80-6)
- 5-cyclopropyl-1-methyl-1H-pyrazol-4-amine (CAS 1393100-83-8)
- 2-Chloro-5-(4-t-butylphenyl)benzoic acid (CAS 926201-32-3)
- 1-tert-Butyl-6-propoxybenzimidazole (CAS 1314988-55-0)
- Tetramethylammonium hydroxide pentahydrate (CAS 10424-65-4)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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