GNE-781, 98% (HPLC) CAS 1936422-33-1
| CAS No. | 1936422-33-1 |
| Molecular Formula | C27H33F2N7O2 |
| Molecular Weight | 525.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including GNE-781, 98% (HPLC).
GNE-781, 98% (HPLC) (CAS 1936422-33-1) is a high-purity analytical reference standard with the molecular formula C27H33F2N7O2 and a molecular weight of 525.59 g/mol.
GNE-781, 98% (HPLC) (C27H33F2N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures GNE-781, 98% (HPLC) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H33F2N7O2 |
| Molecular Weight | 525.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related GNE Standards
- BAY-598, >98% (HPLC) (CAS 1906919-67-2)
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- GSK-2292767, >98% (HPLC) (CAS 1254036-66-2)
- RAF-709, >98% (HPLC) (CAS 1628838-42-5)
Recommended Standards
- (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-4-(tert-butoxycarbonyl)-5-oxopentanoic acid (CAS 111662-65-8)
- N,N'-((3aR,4S,7R,7aS)-5-(benzamidomethyl)-2,2-dimethyl-3a,4,7,7a-tetrahydrobenzo[d][1,3]dioxole-4,7-diyl)dibenzamide (CAS 1998128-29-2)
- 11-(2-((2,2-Dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-5-nitrophenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 1023515-06-1)
- N-Boc-N-bis(PEG3-acid) (CAS 2055023-35-1)
- Terpin Hydrate (750 mg) (CAS 2451-01-6)
- 4-(3-Chloro-4-methylphenyl)-5-((4-methoxyphenoxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 723332-63-6)
- Methyl (1S,5S,6S)-2-oxabicyclo[3.1.0]Hexane-6-carboxylate (CAS 88333-11-3)
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- tert-Butyl 5-bromo-3-chloro-6-nitro-1H-indazole-1-carboxylate (CAS 929617-40-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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