GNE-272, >98% (HPLC) CAS 1936428-93-1
| CAS No. | 1936428-93-1 |
| Molecular Formula | C22H25FN6O2 |
| Molecular Weight | 424.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of GNE-272, >98% (HPLC) is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies GNE-272, >98% (HPLC) (CAS 1936428-93-1), a certified reference material (molecular formula C22H25FN6O2, MW 424.47 g/mol) for analytical method development and quality control.
GNE-272, >98% (HPLC) (C22H25FN6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25FN6O2 |
| Molecular Weight | 424.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related GNE Standards
- ACT-709478, 98% (HPLC) (CAS 1838651-58-3)
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- PSI-352938, >98% (HPLC) (CAS 1231747-17-3)
- AZD-3839, >98% (HPLC) (CAS 1227163-84-9)
- RG-7800, >98% (HPLC) (CAS 1449598-06-4)
- RK-287107, >98% (HPLC) (CAS 2171386-10-8)
- AZD-6642, >98% (HPLC) (CAS 1643809-54-4)
Recommended Standards
- 4-[(4-Fluorophenyl)methyl]-3-{1-[2-(3-methylphenoxy)acetyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775379-05-9)
- (2S,5R,6R)-6-((R)-2-((Furan-2-carbonyl)oxy)-4-methylpentanamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (CAS 54340-65-7)
- 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775335-58-4)
- 2-((4-(N-(2,4-dimethylphenyl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 433310-45-3)
- 2,3,4-Trimethyl-3-pentanol (CAS 3054-92-0)
- 2-((5-Benzyl-3-carbamoyl-4-methylthiophen-2-yl)carbamoyl)benzoic acid (CAS 314281-77-1)
- 2-Fluoro-3-iodo-4-(trifluoromethyl)pyridine (CAS 1227595-15-4)
- (R)-2-(2-Aminoacetamido)succinic acid (CAS 17343-03-2)
- 3-(Ethanesulfonyl)pyrrolidine (CAS 1378472-99-1)
- 4-Demethyl Daunorubicin Hydrochloride (Carubicin HCl) (CAS 52794-97-5)
- 5-Oxohexahydro-1H-pyrrolizine-3-carboxamide (CAS 134023-97-5)
- 3-Bromo-1-morpholinopropan-1-one (CAS 324796-35-2)
- rel-(1R,4R,5R)-5-Hydroxybicyclo[2.2.1]heptan-2-one (CAS 58029-23-5)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
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