4-Chloro-3-hydroxypyridin-2(1H)-one CAS 19365-20-9
| CAS No. | 19365-20-9 |
| Molecular Formula | C5H4ClNO2 |
| Molecular Weight | 145.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-3-hydroxypyridin-2(1H)-one is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloro-3-hydroxypyridin-2(1H)-one (CAS 19365-20-9), a certified reference material (molecular formula C5H4ClNO2, MW 145.54 g/mol) for analytical method development and quality control.
Structurally, 4-Chloro-3-hydroxypyridin-2(1H)-one (C5H4ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 145.54 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3-hydroxypyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4ClNO2 |
| Molecular Weight | 145.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-6-hydroxypyridin-2(1H)-one (CAS 103792-71-8)
- 3-Chloro-1H-pyrrole-2-carboxylic acid (CAS 1053658-09-5)
- 2-Chloro-3-hydroxypyridin-4(1H)-one (CAS 1204295-69-1)
- 2-Chloro-1-oxazol-2-yl-ethanone (CAS 1211536-43-4)
- 2-Chloro-1-oxazol-4-yl-ethanone (CAS 1216314-67-8)
- 5-Chloro-3-methyl-1,2-oxazole-4-carbaldehyde (CAS 1314901-77-3)
- 6-Chloro-3-hydroxypyridin-2(1H)-one (CAS 1420535-82-5)
- 2-Chloro-1-(oxazol-5-yl)ethan-1-one (CAS 1421314-19-3)
Recommended Standards
- 3-chlorofuran-2-carboxamide (CAS 1849195-15-8)
- (E)-N-[(5-chlorofuran-2-yl)methylidene]hydroxylamine (CAS 54376-27-1)
- 4-Chloro-6-hydroxypyridin-2(1H)-one (CAS 1823272-62-3)
- 1-(3-Chloroisoxazol-5-yl)ethan-1-one (CAS 80403-94-7)
- Phenobarbital (CAS 50-06-6)
- 5-(4-Chlorobenzyl)-1H-pyrrole-2-carboxylic acid (CAS 1483054-94-9)
- N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)hexyl)benzothioamide (CAS 117067-53-5)
- N-Butylamphetamine Hydrochloride (CAS 35892-11-6)
- (2-Fluoro-5-(piperidin-1-ylmethyl)phenyl)boronic acid (CAS 1334226-29-7)
- 2-(2-Chloro-6-(difluoromethyl)-4-methoxypyridin-3-yl)acetic acid (CAS 1806898-50-9)
- 6-(Cyanomethyl)-3-(difluoromethyl)-2-hydroxyisonicotinonitrile (CAS 1806948-99-1)
- 1-(3-Fluoropyrrolidin-3-yl)-N,N-dimethylmethanamine (CAS 125032-78-2)
- 3-(2-(1,3-Dioxan-2-yl)ethoxy)propan-1-ol (CAS 101563-40-0)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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