1,3,5,7-Tetramethyl-8-phenyl-4,4-difluorodiazetidine CAS 194235-40-0
| CAS No. | 194235-40-0 |
| Molecular Formula | C19H19BF2N2 |
| Molecular Weight | 324.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,3,5,7-Tetramethyl-8-phenyl-4,4-difluorodiazetidine (C19H19BF2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1,3,5,7-Tetramethyl-8-phenyl-4,4-difluorodiazetidine (CAS 194235-40-0) is a high-purity analytical reference standard with the molecular formula C19H19BF2N2 and a molecular weight of 324.18 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1,3,5,7-Tetramethyl-8-phenyl-4,4-difluorodiazetidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H19BF2N2 |
| Molecular Weight | 324.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 5-(Trifluoromethyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carboxylic acid (CAS 187998-46-5)
- ((2,5-Dichlorophenyl)sulfonyl)-L-proline (CAS 298687-02-2)
- ((2R,3S,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 18354-06-8)
- ((3,4-Dichlorophenyl)sulfonyl)-L-proline (CAS 474376-21-1)
- 3-Amino-4,4,4-trifluoro-2-butenenitrile (CAS 33561-24-9)
- 4-Methoxy-3-(pyrrolidin-1-ylmethyl)benzoic acid hydrochloride (CAS 1185058-72-3)
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