Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate CAS 194282-66-1
| CAS No. | 194282-66-1 |
| Molecular Formula | C18H16ClNO6 |
| Molecular Weight | 377.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 377.78 g/mol gives Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 194282-66-1), molecular formula C18H16ClNO6 and molecular weight 377.78 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (C18H16ClNO6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 377.78 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16ClNO6 |
| Molecular Weight | 377.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- N-(2-chlorophenyl)-2-((3-(trifluoromethyl)phenyl)sulfonyl)acetamide (CAS 339107-39-0)
- 1,3-Dimethyl 2-[(3-chlorophenyl)methyl]-2-(4-nitrophenyl)propanedioate (CAS 685108-27-4)
- 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinaldehyde (CAS 1806908-49-5)
- 5-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)pentan-1-ol (CAS 58241-40-0)
- (R)-2-((R)-3-(Benzo[d][1,3]dioxol-5-yl)-3-((6-methoxynaphthalene)-2-sulfonamido)propanamido)-3-(4-(((2R,6S)-2,6-dimethylpiperidin-1-yl)methyl)phenyl)-N-isopropyl-N-methylpropanamide (CAS 465539-70-2)
- 1-(2-Chloroethyl)-1h-pyrazole-4-carbaldehyde (CAS 864723-36-4)
- Dimethyl (3-(4-chlorophenoxy)-2-oxopropyl)phosphonate (CAS 40665-86-9)
- 1-Boc-4-(2-Aminophenyl)piperazine (CAS 170017-74-0)
- 2-((4-Ethylpiperazin-1-yl)methyl)benzaldehyde (CAS 1443350-32-0)
- Ethyl 3-(6-hydroxypyridazin-3-yl)propanoate (CAS 6484-01-1)
- 4-Chloro-3-(3-fluorophenyl)pyridin-2-amine (CAS 1381941-71-4)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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