5-Chloro-1H-indole-3-carbonitrile CAS 194490-14-7
| CAS No. | 194490-14-7 |
| Molecular Formula | C9H5ClN2 |
| Molecular Weight | 176.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 176.60 g/mol gives 5-Chloro-1H-indole-3-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-Chloro-1H-indole-3-carbonitrile (CAS 194490-14-7), a certified reference material (molecular formula C9H5ClN2, MW 176.60 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 5-Chloro-1H-indole-3-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 176.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN2 |
| Molecular Weight | 176.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-1H-indole-5-carbonitrile (CAS 1034690-30-6)
- 6-Chloro-1H-indole-4-carbonitrile (CAS 1097629-20-3)
- 3-Chloro-1H-indole-6-carbonitrile (CAS 116482-52-1)
- 7-Chloro-1H-indole-4-carbonitrile (CAS 1167056-48-5)
- 3-Chloro-4-(cyanomethyl)benzonitrile (CAS 1261672-27-8)
- 7-Chloro-1H-indole-2-carbonitrile (CAS 1264481-38-0)
- 5-chloro-1H-indole-2-carbonitrile (CAS 1374452-17-1)
- 4-Chloro-1H-indole-5-carbonitrile (CAS 1427409-07-1)
Recommended Standards
- 3-(2-chloroethyl)-5-methylimidazolidine-2,4-dione (CAS 1909305-48-1)
- 6-Chloro-1H-indole-3-carbonitrile (CAS 194490-17-0)
- 3-(2-Chloroethyl)-5-(methoxymethyl)-1,2,4-oxadiazole (CAS 1824274-24-9)
- (Z)-3-Chloro-2-formyl-but-2-enoic acid ethyl ester (CAS 31357-78-5)
- Trimethyl(vinyl)ammonium chloride (CAS 6018-82-2)
- methyl 3-hydrazinobicyclo[1.1.1]pentane-1-carboxylate;hydrochloride (CAS 2149634-45-5)
- (2-fluoro-4-hydroxyphenyl)boronic acid (CAS 1376989-43-3)
- 1-Bromo-2-fluoro-4-(prop-2-yn-1-yloxy)benzene (CAS 1483672-33-8)
- 1-(2-Chloro-6-fluorobenzyl)-3-isothiocyanato-1h-1,2,4-triazole (CAS 832739-26-1)
- 2-(1-(Tert-butoxycarbonyl)azetidin-3-yl)-3-methylbutanoic acid (CAS 1781859-84-4)
- tert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1351094-00-2)
- 3-Isothiocyanato-5-methylpyridine (CAS 52648-32-5)
- 3-Methylsulfonyl-2,2',4',5,5',6-hexachlorobiphenyl (CAS 149949-88-2)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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