2-Bromophenylacetonitrile CAS 19472-74-3
| CAS No. | 19472-74-3 |
| Molecular Formula | C8H6BrN |
| Molecular Weight | 196.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromophenylacetonitrile (C8H6BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Bromophenylacetonitrile (CAS 19472-74-3), molecular formula C8H6BrN and molecular weight 196.04 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN |
| Molecular Weight | 196.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Bromo-N-(2-methoxyethyl)acetamide (CAS 174215-37-3)
- (R)-2-Amino-5-bromopentanoic acid (CAS 212690-30-7)
- 4-Bromobenzyl Cyanide (CAS 16532-79-9)
- 1-Bromo-5-nitropentane (CAS 82655-19-4)
- 4-((1H-Benzo[d]imidazol-2-yl)amino)-4-oxobutanoic acid (CAS 54346-70-2)
- 2-Amino-7-methoxy-[1,2,4]triazolo[1,5-a]pyridine (CAS 1239648-98-6)
- 2-(3-Bromophenyl)-4,6-diphenylpyrimidine (CAS 864377-22-0)
- (4-(Dimethylamino)phenyl)(4-phenylpiperazin-1-yl)methanone (CAS 333350-91-7)
- Methyl 4-(4-hydroxyphenyl)-2-methoxybenzoate (CAS 1820605-04-6)
- Ethyl 3-(N-(3-ethylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 932464-28-3)
- 3-Chloroquinoxaline-2-carboxamide (CAS 40254-88-4)
- 1-Oxo-2-(o-tolyl)-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid (CAS 436810-98-9)
- N-(2-Fluoro-5-methylbenzyl)-N-methylamine (CAS 1178036-90-2)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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