3-Bromo-5-nitrobenzo[b]thiophene CAS 19492-95-6
| CAS No. | 19492-95-6 |
| Molecular Formula | C8H4BrNO2S |
| Molecular Weight | 258.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-5-nitrobenzo[b]thiophene (CAS 19492-95-6) is a high-purity analytical reference standard with the molecular formula C8H4BrNO2S and a molecular weight of 258.09 g/mol.
3-Bromo-5-nitrobenzo[b]thiophene (C8H4BrNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Bromo-5-nitrobenzo[b]thiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4BrNO2S |
| Molecular Weight | 258.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 2-Bromo-3-nitro-1-benzothiophene (CAS 100949-37-9)
- 5-Bromo-6-fluoro-3,3-dimethylindolin-2-one (CAS 1017860-04-6)
- 1-(2-Bromo-4-fluorophenyl)pyrrolidin-2-one (CAS 1037150-18-7)
- 1-(3-Bromo-5-fluorophenyl)pyrrolidin-2-one (CAS 1100508-97-1)
- 3-Bromo-1-(4-fluorophenyl)pyrrolidin-2-one (CAS 1100756-25-9)
- 3-Bromo-N-cyclopropyl-5-fluorobenzamide (CAS 1147712-88-6)
- 4-(4-Bromo-2-fluorophenoxy)butanenitrile (CAS 1152534-11-6)
- 5-Bromo-1,3-benzothiazole-2-carboxylic acid (CAS 1187928-52-4)
Recommended Standards
- 5-Bromothieno[2,3-b]pyridine-3-carboxylic acid (CAS 1935928-11-2)
- (R)-4-(3-bromo-5-fluorophenyl)pyrrolidin-2-one (CAS 2306247-63-0)
- 3-bromo-1-(2-fluorophenyl)pyrrolidin-2-one (CAS 188533-10-0)
- 1-(4-Bromo-2-fluorophenyl)pyrrolidin-2-one (CAS 625446-50-6)
- (s)-2-Amino-2-(4-(diethylamino)phenyl)ethan-1-ol (CAS 1212818-50-2)
- 2,2-Difluoro-2-(methylsulfinyl)acetic acid (CAS 1536017-62-5)
- 5-Chloro-2-methyl-4-(trifluoromethyl)aniline (CAS 1805645-04-8)
- (3-Fluorobenzyl)(phenyl)sulfane (CAS 712301-51-4)
- (E)-4-((E)-3-phenylallylidene)isochromane-1,3-dione (CAS 69139-24-8)
- 3-(2-aminoethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one hydrochloride (CAS 879635-07-1)
- Ethyl3-amino-5-bromo-pyridine-2-carboxylate (CAS 1334405-60-5)
- 1,3-Bis(2-(4-cyanatophenyl)propan-2-yl)benzene (CAS 127667-44-1)
- Dexrazoxane Impurity 39 (CAS CATO-C4X-202039)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com