2-Chloro-6-nitropyrazine CAS 195073-19-9
| CAS No. | 195073-19-9 |
| Molecular Formula | C4H2ClN3O2 |
| Molecular Weight | 159.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-nitropyrazine (CAS 195073-19-9) is a high-purity analytical reference standard with the molecular formula C4H2ClN3O2 and a molecular weight of 159.53 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-6-nitropyrazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 159.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-6-nitropyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H2ClN3O2 |
| Molecular Weight | 159.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-chloro-5-nitropyrimidine (CAS 10320-42-0)
- 5-Chloro-2-nitropyrimidine (CAS 120583-91-7)
- 4-Chloro-5-nitropyrimidine (CAS 150943-50-3)
- 4-Chloro-1,3,5-triazine-2-carboxylic Acid (CAS 1550823-05-6)
- 2-Chloro-3-nitropyrazine (CAS 87885-43-6)
- 4-Chloro-5-fluoropicolinaldehyde (CAS 1060802-32-5)
- 4-Chloro-5-fluoro-pyridine-3-carbaldehyde (CAS 1060802-34-7)
- 6-Chloro-4-fluoropyridine-3-carbaldehyde (CAS 1060809-20-2)
Recommended Standards
- Relugolix Impurity 32 (CAS 1334511-36-2)
- 2-Chloro-4-fluoropyridine-3-carbaldehyde (CAS 1060809-21-3)
- 3,3,3-trichloro-2-methylprop-1-ene (CAS 4749-27-3)
- 3-Chloro-2-fluoroisonicotinaldehyde (CAS 1149587-02-9)
- 1-(1,3-Dioxaindan-5-yl)butan-2-ol (CAS 113283-34-4)
- tert-butyl N-(3-{[(3,5-dichlorophenyl)methyl]amino}propyl)carbamate hydrochloride (CAS 1803604-71-8)
- (2E)-3-(2,4-Dichlorophenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (CAS 1352346-90-7)
- Ethyl (R)-3-amino-3-(naphthalen-1-yl)propanoate (CAS 275826-40-9)
- 1-Bromo-3-fluoro-2-(3-fluorophenyl)benzene (CAS 1233367-30-0)
- Ethyl 4-((6-methylpyrazin-2-yl)oxy)benzoate (CAS 906353-03-5)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(acetamidothio)-3-methylbutanoic acid (CAS 1246647-73-3)
- Tetrahydro-2-oxo-3-furancarbonitrile (CAS 27512-26-1)
- Methyl (E)-3-(4-(octyloxy)phenyl)acrylate (CAS 99196-57-3)
- Insulin Detemir (CAS 169148-63-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com