6-(((3-Chloropyridin-2-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,5-dione CAS 1951451-52-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1951451-52-7
Molecular FormulaC12H11ClN2O4
Molecular Weight282.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(((3-Chloropyridin-2-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,5-dione CAS 1951451-52-7 chemical structure

Description

6-(((3-Chloropyridin-2-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,5-dione (CAS 1951451-52-7), molecular formula C12H11ClN2O4 and molecular weight 282.68 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-(((3-Chloropyridin-2-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,5-dione (C12H11ClN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(((3-Chloropyridin-2-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11ClN2O4
Molecular Weight282.68 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1996
Halogen ContentCl-containing
Nitrogen Atoms2

Related Chloropyridin Standards

Recommended Standards

Why CATO?