Raloxifene EP Impurity C CAS 195454-31-0
| CAS No. | 195454-31-0 |
| Molecular Formula | C28H27NO5S |
| Molecular Weight | 489.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Raloxifene EP Impurity C (CAS 195454-31-0), a pharmacopoeial impurity reference standard (molecular formula C28H27NO5S, MW 489.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Raloxifene EP Impurity C is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 489.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C28H27NO5S |
| Molecular Weight | 489.58 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Raloxifene Standards
- Raloxifene 6-Monomethyl Ether (CAS 178451-13-3)
- Raloxifene 4-Monomethyl Ether (CAS 185415-07-0)
- Raloxifene D4 (CAS 1185076-44-1)
- Raloxifene Bismethyl ether (CAS 84541-38-8)
- Raloxifene Impurity 12 (CAS CATO-C4X-174312)
- Raloxifene Impurity 11 (CAS CATO-C4X-174311)
- Raloxifene (CAS 84449-90-1)
- Raloxifene Impurity 13 (CAS 185416-01-7)
Recommended Standards
- Eplerenone Impurity 37 (CAS CATO-C4X-163037)
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- N-(5-(N,N-Diethylsulfamoyl)-2-(4-fluorophenoxy)phenyl)-2-(methylthio)nicotinamide (CAS 949967-51-5)
- N-(2,5-Dimethoxyphenyl)-2-((4-phenyl-5-((p-tolylamino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332907-12-7)
- Prilocaine impurity 52 (CAS CATO-C4X-193452)
- Dolutegravir O-Methyl Impurity (CAS 1335210-35-9)
- Pranoprofen Impurity 41 (CAS CATO-C4X-181141)
- (S)-1-amino-1-cyclopropyl-2-methylpropan-2-ol hydrochloride (CAS 1363408-33-6)
- Tauroursodeoxycholic acid Impurity 44 (CAS 88725-39-7)
- Fluoxetine EP Impurity C HCl (CAS 79088-29-2)
- N-Hydroxy-2-((4-isopropoxyphenyl)sulfonyl)acetimidamide (CAS 886499-43-0)
- 1-Chloro-5-iodo-2,4-dimethoxybenzene (CAS 96694-60-9)
- CAS 251459-09-3 (CAS 251459-09-3)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
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