tert-Butyl 2,6-difluoronicotinate CAS 1956375-96-4
| CAS No. | 1956375-96-4 |
| Molecular Formula | C10H11F2NO2 |
| Molecular Weight | 215.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures tert-Butyl 2,6-difluoronicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
tert-Butyl 2,6-difluoronicotinate (CAS 1956375-96-4), molecular formula C10H11F2NO2 and molecular weight 215.20 g/mol, is a CATO reference standard with documented purity and traceability.
tert-Butyl 2,6-difluoronicotinate (C10H11F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F2NO2 |
| Molecular Weight | 215.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl 2,5-difluoronicotinate (CAS 1956331-66-0)
- (2,4-Dihydroxyphenyl)(pyridin-3-yl)methanone (CAS 64302-24-5)
- 7-Acetylquinoline-3-carboxylic acid (CAS 1956328-33-8)
- (2R,3R,4S,5S)-5-(3-Ethylisoxazol-5-yl)tetrahydrofuran-2,3,4-triol (CAS 607376-21-6)
- 1-[4-(Methylsulfonyl)phenyl]piperidine-4-carbohydrazide (CAS 942474-58-0)
- 2-Isopropyl-7H-furo[3,2-g]chromen-7-one (CAS 1215-38-9)
- (2S,3S,4R,5R)-2-(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol hydrochloride (CAS 222631-44-9)
- (3R,7AR)-3-PHENYLTETRAHYDROPYRROLO[1,2-C]OXAZOL-5(3H)-ONE (CAS 1820583-17-2)
- Spermine Phosphate Hexahydrate (CAS 58298-97-8)
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- Butyl 3,7-dichloroquinoline-8-carboxylate (CAS 381686-74-4)
- N-(2-aminophenyl)-N-(4-methylphenyl)amine hydrochloride (CAS 384371-27-1)
- Etrasimod Impurity 74 (CAS CATO-C4X-321474)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com