Methyl 4-bromo-1-cyclopropyl-3-methyl-1H-indole-6-carboxylate CAS 1956380-38-3
| CAS No. | 1956380-38-3 |
| Molecular Formula | C14H14BrNO2 |
| Molecular Weight | 308.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 4-bromo-1-cyclopropyl-3-methyl-1H-indole-6-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 4-bromo-1-cyclopropyl-3-methyl-1H-indole-6-carboxylate (CAS 1956380-38-3) is a high-purity analytical reference standard with the molecular formula C14H14BrNO2 and a molecular weight of 308.17 g/mol.
The molecular framework of Methyl 4-bromo-1-cyclopropyl-3-methyl-1H-indole-6-carboxylate (C14H14BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-bromo-1-cyclopropyl-3-methyl-1H-indole-6-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14BrNO2 |
| Molecular Weight | 308.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- 1,2-Bis(trifluoromethyl)-3-(difluoromethoxy)-4-ethylbenzene (CAS 1805573-72-1)
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- 1-(tert-Butyl) 2-methyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate (CAS 334999-29-0)
- (R)-3-Chloro-1-methyl-pyrrolidine (CAS 1354017-10-9)
- 2-amino-5-ethylthiophene-3-carboxylic acid (CAS 55502-94-8)
- Tisocalcitate (CAS 156965-06-9)
- 4,5,6,7-Tetrahydro-2H-indazol-6-amine (CAS 74197-22-1)
- 2,6-difluoro-3,4-diiodopyridine (CAS 685517-78-6)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d][1,2,3]triazole (CAS 2379560-98-0)
- 2-(2-(Azepan-1-yl)-4-mesitylthiazol-5-yl)acetic acid (CAS 1443289-67-5)
- 2-(Pyrazin-2-yl)malonaldehyde (CAS 13481-00-0)
- (4-(Benzyloxy)-2,6-difluorophenyl)boronicacid (CAS 156635-89-1)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
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