Methyl 4-bromo-1-cyclopropyl-3-formyl-1H-indole-6-carboxylate CAS 1956381-75-1
| CAS No. | 1956381-75-1 |
| Molecular Formula | C14H12BrNO3 |
| Molecular Weight | 322.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 4-bromo-1-cyclopropyl-3-formyl-1H-indole-6-carboxylate (C14H12BrNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Methyl 4-bromo-1-cyclopropyl-3-formyl-1H-indole-6-carboxylate (CAS 1956381-75-1) is a high-purity analytical reference standard with the molecular formula C14H12BrNO3 and a molecular weight of 322.15 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 4-bromo-1-cyclopropyl-3-formyl-1H-indole-6-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12BrNO3 |
| Molecular Weight | 322.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1,1,1-Trifluoro-10-iododecane (CAS 1965305-16-1)
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- (4-Bromophenyl)methyl N-[(E)-2-(furan-2-yl)ethenyl]carbamate (CAS 338399-79-4)
- Methyl 6-(Benzyloxy)-5-bromopyridine-2-carboxylate (CAS 1493800-02-4)
- Dimethyl 4-aminoheptanedioate (CAS 873843-61-9)
- 4-(trifluoromethyl)-1,3-thiazole (CAS 101048-75-3)
- 1,1,3,3-Tetramethyl propane-1,1,3,3-tetracarboxylate (CAS 28781-92-2)
- 2-(3-Bromophenyl)-1,1,1-trifluoropropan-2-ol (CAS 122243-30-5)
- 1,2-Dibromo-3,6-dichlorobenzene (CAS 100191-22-8)
- 5-(Chloromethyl)-1-isobutyl-1H-imidazole (CAS 781599-92-6)
- (S)-1-phenylethanamine (S)-2-((tert-butoxycarbonyl)(methyl)amino)-3-methyl-3-phenylbutanoate (CAS 676487-36-8)
- methyl 1H-imidazole-2-carboxylate hydrochloride (CAS 2060006-00-8)
- Febuxostat Impurity 80 (CAS CATO-C4X-116280)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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